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Description

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In global terms, hypothalamic pathways involved in autophagy, neurotransmitter release, cytoskeletal remodeling (RHO GTPases signaling), vesicle-mediated transport and intracellular signaling (PI3K/AKT activation) were upregulated in PWA mice treated with GLP1/E, while pathways related with vesicle transport, oxidative stress, DNA repair, metabolism and immune system were downregulated by GLP1/E treatment (Fig

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Therefore, understanding the biochemical mechanisms involving vitamin B12 during patient treatment is crucial for neurochemistry and medicine

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Such efforts hold the potential to transform current therapeutic paradigms, offering hope for precision medicine in the fight against neurodegeneration

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