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It suggests theres an additive effect of these two medications, said Andrew Saxon, an addiction psychiatrist at the University of Washington who was not involved with this study, potentially because liraglutide and buprenorphine target different mechanisms

Additionally, the FDA recommends that these medications not be taken during pregnancy and be discontinued at least two months prior to pregnancy, because studies in rats, rabbits, and monkeys demonstrated that animals treated with these medications had higher rates of miscarriage, were born smaller, and were more likely to have birth defects

10.1038/s41467-021-27414-1 Nat Commun

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