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Storage and Handling Requirements Cagrilintide requires specific storage conditions to maintain potency: Refrigeration Store unopened vials at 2-8C (36-46F) Temperature stability Once in use, may be kept at room temperature (below 30C) for up to 4 weeks Light protection Keep in original packaging to protect from light exposure Freezing prohibition Never freeze
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However, it is associated with significant incidences of infusion reactions, anaphylaxis, methemoglobinemia, and hemolysis, particularly in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency
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However, once these patents expire, generic manufacturers could enter the market relatively quickly, as the synthesis of a small molecule like orforglipron does not require the specialized SPPS facilities and expertise needed for generic peptide production