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If you had to pick one: GHK-Cu has broader biological reach (roughly 4,000 genes modulated versus 300-500 for retinol) [3] and a higher responder rate for collagen improvement in the only direct comparison

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Component ratios vary by vendor

Benefits Removes dark spots: The potent, water-based formula removes dark spots, blemishes and hyperpigmentation from the skin making it look visibly brighter

Int J Biosci (IJB)