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CAT No: 10-101-343 CAS No: 1401708-83-5 Synonyms/Alias: dihexa;1401708-83-5;L-Isoleucinamide, N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-hexanoic-Tyr-Ile-(6) aminohexanoic amide;9WYX65A5C2;PNB-0408;(2S,3S)-N-(6-amino-6-oxohexyl)-2-[[(2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanamide;6-(2-(2-Hexanamido-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)hexanamide;6-[(2S,3S)-2-[(2S)-2-hexanamido-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]hexanamide;Hexanoyl-Tyr-Ile-Ahx-NH2;UNII-9WYX65A5C2;Dihexa (PNB-0408)?;DTXSID701032895;GLXC-25923;ATH-1001;AKOS040759118;CS-6864;DA-62870;HY-16969;PNB-0408

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The therapeutic dose is approximately 300-fold below the toxic threshold according to animal studies

The compound crosses the blood-brain barrier efficiently after oral administration and demonstrates sustained cognitive benefits even after treatment cessation, suggesting true structural enhancement rather than temporary stimulation

Parkinsonism Relat Disord 93:7784

Alvarado JL, Leschot A, Olivera-Nappa A, Salgado AM, Rioseco H, Lyon C, Vigil P