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This guide compares the clinical evidence on side effects across the main GLP-1 options available in the UK

For compounded semaglutide, remove the orange cap from the needle and hold the syringe upright, then insert it into the middle of the rubber stopper that contains the medication

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The documented route is subcutaneous a shallow injection into the fat layer just under the skin (abdomen, flank or thigh), using a fine insulin needle

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These are medians for individual episodes, not time to permanent resolution