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Aust N Z J Psychiatry 2009;43:594-605
The liver processes copper continuously as part of normal metabolism
& Skerka, C
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Bai H, Yang B, Yu W, Xiao Y, Yu D, Zhang Q
Although studies have confirmed that the three components form a positive-feedback loop that drives DR progression and that antioxidant therapy can alleviate DR pathology, the key molecular triggers that initiate the loopsuch as the cell-specific mechanisms by which hyperglycemia induces excessive ROS production in different retinal cellsremain poorly defined
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