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Factors that likely influence individual response include baseline heart rate, cardiovascular fitness level, autonomic nervous system tone, body composition, and potentially genetic variations in glucagon receptor density or sensitivity
A secondary analysis of these findings discovered that semaglutide significantly improves heart failure symptoms in both males and females, leading to greater weight loss in the latter
Though several factors could be contributing to the lower rates of weight loss in real-world examples, GLP-1 drugs still result in significant reductions in body weight
Full details will be published at an upcoming medical congress and in a peer-reviewed journal
