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Abstract Background Guidelines recommend combination therapy with glucagonlike peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2is) for cardiorenal risk reduction in people with type 2 diabetes (T2D)

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Some nausea can still occur in a portion of users, a faint echo of its Melanotan origins, but the pigmentation risks have been engineered out