The effect is gradual and works best over 3 to 6 months
One of the strongest criticisms of his regime, though, is that while he is improving on the typical biomarkers of age strength, bone density and hair thickness he is not slowing ageing in any meaningful way
At week 4, women in the treatment group displayed improved skin elasticity (+12.7%), reduced wrinkle volume (16.5%), decreased transepidermal water loss (10.8%), increased hydration (+3.5%), and enhanced collagen density compared with baseline values (measured via specialized skin analysis instrumentation)
That said, it doesnt really have such a big role in athletes and other high-performance individuals
However, if you are ill, high doses of vitamin B12 that you might receive to treat a deficiency may cause some symptoms, such as: What to avoid while taking B12
conservative dosing protocols are strongly recommended [2]