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Front Pharmacol 9:339
Expert consensus on diagnosis and treatment of diabetic neuropathy (2021 edition)
Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: a randomized, placebo-controlled trial
In contrast, daily bolus injections of TZP/Sema showed greater inter-animal variability, suggesting less consistent glycemic control
Timing can vary depending on the severity of symptoms, the underlying cause, diet, medications, stress levels, and whether the gut issue is inflammatory, infectious, structural, or functional
[1] Contact your GP or NHS 111 if: Gastrointestinal side effects persist beyond the first few weeks or worsen over time Diarrhoea persists for more than a few days or is accompanied by fever Constipation becomes severe or does not respond to dietary measures and over-the-counter remedies You experience unexplained weight loss beyond expected therapeutic effects Symptoms significantly impact your quality of life or ability to maintain nutrition You have concerns about any new or unusual symptoms Patients with known diverticular disease should maintain regular contact with their healthcare team and report any changes in bowel habits or abdominal symptoms promptly
