Hypertensive patients have been observed to produce high levels of hydrogen peroxide, superoxide anion, and NO in leukocytes [290,291,292], exhibit elevated lipid peroxidation in erythrocytes, and display elevated concentrations of 8-isoprostanes in plasma [293]
Risk is almost always a product of self-sourcing unregulated vials , poor reconstitution , non-sterile technique , or wrong dose for goal - all of which we see in patients who come to us after online DIY protocols
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