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For Indian skin (Fitzpatrick IVVI) Retinol may carry heightened irritation risk in Fitzpatrick IV-VI skin types and requires cautious introduction due to increased melanin content and barrier sensitivity

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Stimulation of these receptors could theoretically increase sympathetic outflow, leading to a mild chronotropic (heart rate-increasing) effect

These symptoms can be uncomfortable and may worsen if you already have anxiety around physical health symptoms, as is common with some people with OCD

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