semaglutide patent expiry us 2031 Abel + Imray Semaglutide — the powerhouse ingredient

Lifespan extension in animal studies Rodent studies (most extensive data): Mice lifespan increased 20-42% with Epithalon Rats showed 12-25% lifespan extension Both maximum lifespan and median lifespan increased Healthspan (healthy years) improved even more Similar to effects seen with caloric restriction but without dietary limitation Study examples: Mechanisms of lifespan extension: Telomere preservation preventing cellular senescence Reduced oxidative damage to tissues Improved immune function preventing infections Better hormone regulation (pineal, reproductive) Reduced age-related diseases (cancer, cardiovascular) Human lifespan effects (theoretical): No completed human lifespan studies (require decades) If similar extension: 20% of 80-year lifespan = 16 additional years More realistically: Healthspan improvement more achievable than lifespan Quality of life in later years potentially enhanced Similar goals as other longevity interventions Limitations of animal data: Rodents humans (metabolism, telomere biology differ) Controlled lab conditions vs real-world human life Optimal dosing in humans unknown Long-term safety in humans not established Need rigorous human trials for validation Compare to other longevity approaches like growth hormone peptides at SeekPeptides

Taking weight loss medication alongside a healthy diet and regular exercise is backed by scientific evidence

Why do some people need compounded drugs

Given that GLP-1RAs are demonstrating efficacy in diseases beyond weight loss and diabetes, their use is only going to increase

Haywood CJ, Prendergast LA, Lim R, Lappas M, Lim WK, Proietto J

Its still in clinical trials, so you cant be prescribed it yet, but research on retatrutide as a treatment for type 2 diabetes and weight management is showing promising results