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GSSG sensitized hepatocytes to TNF-mediated cytotoxicity via the induction of IKK- glutathionylation and subsequent NF-B suppression NF-B activation plays a critical role in protecting hepatocytes from TNF-mediated cytotoxicity
2020 Sun, L et col
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[] Arsenic can also cause thiamine deficiency through the inhibition of the conversion of thiamine to succinyl- and acetyl-coenzyme A
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The mechanism is fundamentally different
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