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GLP-1 receptor agonists are licensed for type 2 diabetes and weight management, not specifically for cholesterol reduction

The ability to cross the rat placenta has been described as low and very limited for sotagliflozin and empagliflozin respectively

Each one of these agents will need to be carefully scrutinised to ensure they preserve or exceed the benefits and safety profile of GLP-1RA alone, without introduction of unanticipated new liabilities impacting therapeutic safety

The limited sample size significantly hinders the interpretation of the results

However, certain circumstances may prompt a provider to recommend more frequent monitoring or reassessment: Patients on liraglutide (Saxenda) may still require daily injections due to the drugs pharmacokinetics