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Constitutive MAPK phosphorylation and pharmacodynamic inhibitio of MEK/MAPK in relapsed/refractory primary acute myelogenous leukemia (AML) cells
That single interaction has downstream effects across several healing pathways: it supports stem-cell migration to injury sites, promotes angiogenesis (like BPC-157, but through a different mechanism), and dampens inflammatory signaling during the repair phase
Katoh, K
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Significant vomiting or diarrhea can lead to dehydration and acute kidney injury
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