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This sensation, called paresthesia, can result from nerve involvement related to a B12 deficiency, often in the hands, legs, or feet
*Correspondence: Daoyu Guo, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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As NOX is expressed at relatively high levels in the islet beta cell, relative to other islet cells, potential therapies based on targeting NOX in the islet may be beneficial for maintaining beta cell function and integrity in conditions of high glucose, lipid or inflammatory challenge, and therefore could be effective in type 2 diabetes treatment
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