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Glutathione naturally decreases with agebut so will muscle, collagen, and maybe even cognition

As NAD levels fall, these essential processes slow down, which has been linked to signs of aging, including cognitive decline and metabolic disease

4F, G), potentially enhancing protection from the proteotoxic stress triggered by mitoribosomal decay and the ensuing cell cycle arrest 17

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Therefore, comprehensive consideration of the overall outcomes should be given when developing therapeutic models that regulate global redox states