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They still get sore, stiff, and fatigued, even if they keep pushing
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This pre-cliff portfolio construction identifying successor products, acquiring diversifying revenue streams, and managing investor expectations through the transition is the financial equivalent of building a second cliff upstream that produces new revenue as the first cliff collapses underneath you
Moreover, quantitative sex-related differences in therapeutic response and adverse effects highlight the need for sex-stratified analyses, which are still lacking in pediatric studies
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