Collectively, while ferroptosis plays a significant role in the pathogenesis of both TMJ OA and KOA, the specific effects may differ due to the distinct tissue characteristics, mechanical stress, and inflammatory environments of TMJ and knee
Based on preclinical studies, a systematic review of the neuroprotective mechanisms of GLP-1RA-based therapy in ischemic stroke [67] has shown that administration of drugs of this family before, during, or after an experimental stroke in animals with and without diabetes modulates an acute inflammatory response secondary to brain ischemia, reducing inflammation, endothelial dysfunction and excitotoxicity, as well as decreasing oxidative stress and apoptosis
menciona que casi no hay reportes de reacciones adversas y sugiere que podra ser una herramienta prometedora para lesiones hipovasculares)pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov
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Castro-Dopico, T