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Pennone V, Angelini E, Sarlah D, Lovati AB
Brain creatine depletion in vegetarians
Patients who don't track reconstitution dates, store vials in the refrigerator door, or skip temperature monitoring are injecting expensive saline with no measurable benefit
Reducing the dose to 3 mg daily or administering earlier in the evening rather than at bedtime may help
Denmeade, S
This modification dramatically reduces binding to IGF-binding proteins (IGFBPs), extending its half-life from ~15 minutes (native IGF-1) to 2030 hours
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