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The Food and Drug Administration (FDA) has updated its labeling for the diabetes drug Ozempic to include a warning about a condition that could lead to blocked intestines, a potentially fatal side effect, following reports by consumers

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Balanced Perspective: Conditional Game Changer The evidence suggests that GLP-1 agonists represent a conditional game changertransformative for appropriate patients with adequate access and support, but with significant limitations that prevent universal application

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Specific warnings include the risk of aspiration for patients, the need for patients to inform their anaesthetist they are taking these medications, and for anaesthetists to consider the heightened risk of aspiration and to manage such patients accordingly

In the short term, however, a too rapid reduction in blood sugar (HbA1c value), as is often achieved with Ozempic, can be dangerous