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This stability property was observed early and supported the use of oral and intragastric dosing routes in a number of animal experiments a meaningful characteristic in preclinical research design

L-arginine is the direct substrate for nitric oxide synthase (NOS), the enzyme that produces NO

- Duration: 4-6 weeks (loading) + 4-6 weeks (maintenance)

This method allows for better absorption compared to taking oral supplements, especially beneficial for those with absorption issues.

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An MTT assay was performed next by seeding tendon fibroblast in each well of 24-well culture plates