The gut microbiome, a complex ecosystem, interacts with the host to influence the health of various organs, including the liver 36,37
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It is one of the first inflammatory signals released when the immune system perceives a threat, and in psoriasis, it acts as a master switch that amplifies virtually every other inflammatory pathway involved
Their ability to migrate, proliferate, and secrete ECM is essential for effective dermal tissue regeneration 69
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Mechanistic synergy: GLP-1 agonists such as semaglutide slow gastric emptying, suppress glucagon, and increase insulin, while cagrilintide enhances satiety and further slows digestion via amylin pathwaystogether providing complementary effects (The Innovation