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Some people manage glucose for years without mealtime insulin, while others eventually need meal coverage because insulin resistance or reduced insulin production makes food-related spikes harder to control

Primary endpoint The primary endpoints are alteration of transcriptomic profile of human tongue tissue as changes in expression level from baseline to follow up after 16 weeks of treatment, measured by RNA sequencing, and change in taste sensitivity as detected by chemical gustometry

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In cancer cells, the upregulation of anti-apoptotic mediators allows cells to evade apoptosis