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The consensus among diabetes specialists and GPs is that Mounjaro should be used as part of a comprehensive diabetes management strategy that prioritises lifestyle modificationsincluding a balanced diet, regular physical activity, and weight managementalongside pharmacological treatment
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Theyll have more choice.
This aspect was important considering that GLP-1 has key interactions with GLP-1R at both ends of the peptide 27,30
Douglas and Channon, 2014
[82] The trial reported cumulative occurrence of major adverse cardiovascular events, a primary end-point event of the trial, for 569 of the 8803 patients in the semaglutide group, which were 6.5% of the participants, and for 701 of the 8801 patients in the placebo group, which were 8% of the participants, showing relative 18.8% less major adverse cardiovascular events, such as death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke, occurring for participants who had received semaglutide in the trial relative to those who had received placebo over the course of around 48 months, or 34.213.7 months, which was the mean (SD) total duration of the participants in either group's exposure to the placebo or semaglutide during the trial
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