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However, FFAR3 is much more enriched in L-cells of the small intestine (191, 193)

Once people stop taking weight-loss medications, the hunger-curbing effects of the drug are removed but their "food environment," such as ultra-processed foods, remains, and weight tends to return, said Dana Small, a professor at McGill University who holds a Canada Excellence Research Chair in metabolism and the brain

Any minor side effects, such as mild fatigue or water retention, often subside after the body adjusts to the therapy

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In aging heart tissue, liraglutide is reported to activate IRS1/eNOS/PKG pathways, restoring mitochondrial function by improving mitochondrial membrane potential and reducing oxidative stress (Durak and Turan, 2023)

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