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It is known that the CV protection effect of GLP-1RAs have been proven through eight large-scale clinical studies, including Evaluation of LIXisenatide in Acute coronary syndrome (ELIXA) [66], LEADER [44], Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN)-6 [67], Exenatide Study of Cardiovascular Event Lowering (EXSCEL) [68], Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes) [69], Researching Cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) [70], Peptide Innovation for Early Diabetes Treatment (PIONEER) 6 [67,71], and AMPLITUDE-O [51]
They dont do the work themselves
Ali, Hepatoprotective activity of the ethanolic extract of Ficus carica Linn
The result is a more controlled, efficient healing process with reduced collateral tissue damage
Peripheral cytokines and activated immune cells enter the CNS through a weakened BBB, increasing microglial activation, ROS generation, and neuronal death in the substantia nigra [71] (Fig
Any discrepancies in data extraction were resolved by reference to the original article and discussion between the researchers
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