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Evidence-based recommendations are critical to ensure the safe and efficient use of these medications in the treatment of obesity as their use continues to increase

Once or twice daily is standard

Dulaglutide Brand name Trulicity

With Melatonin: If using low-dose melatonin (0.3 to 0.5 mg), take melatonin 60 to 90 minutes before bed, then DSIP at 30 minutes

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Some patients may have better-supported FDA-approved treatments available