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Simultaneously, GLP-1 treatment upregulates the expression of ABCA1, thereby repairing the cholesterol efflux from islet -cells that have sustained damage by lipotoxicity, reducing the cellular cholesterol content, improving cellular lipid deposition, and restoring islet -cell function, which is consistent with the results of previous studies (Murao et al., 2009
What dietary approach will best support maintenance during this transition
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Participants in studies have recorded up to a 20% loss of body weight over a span of months
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