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The Immediate Phase: First 24 to 48 Hours For patients with a significant deficiency, the first couple of days can feel like a meaningful change

Commonly reported side effects include mild pain, swelling, or itching at the injection site and sometimes nausea

Sublingual B12 bypasses intestinal absorption issues and potential barriers caused by genetic variants, which makes it a more accessible treatment option for vitamin B12 deficiency

PMID 35691683

A single injection takes only a few minutes, making it one of the most time-efficient supplementation methods available

Taking stimulants, ADHD medication, pseudoephedrine or other sympathomimetics