Taffet, all at Baylor College of Medicine
Hypertension (Dallas, Tex: 1979
More research is needed to determine the best approach to monitoring and managing these patients once the medication is discontinued. According to Maya and colleagues, current evidence on links between GLP-1s and pregnancy complications remain limited, conflicting and subject to residual confounding by indication or selection and recall bias. They added that if gestational weight gain is a result of GLP-1 discontinuation before or early during pregnancy, negative outcomes for the parent-child dyad could result. In the retrospective analysis, the researchers assessed outcomes among 149,790 singleton pregnancies delivered between June 1, 2016, and March 31, 2025
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(34) Given the increased risk of sarcopenia, osteoporosis, and frailty in older adults, future research should explore the long-term effects of GLP-1 receptor agonists on musculoskeletal health in this population, alongside their established systemic benefits
In addition to the regulation of eNOS activity, Cav-1 also can modulate the activation of VEGFR2