Site rotation: If using injection routes, rotate sites to avoid localized tissue effects
Dowlati A, Cervantes A, Babu S, Hamilton EP, Wong SF, Tazbirkova A, et al
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It is generally safe and well-tolerated, with no toxic effects reported at higher doses
Higher doses and longer duration of GLP-1 RAs treatment were also associated with increased risk of gallbladder or biliary diseases, although the association was not statistically significant
FDA labels specifically warn about this risk