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demonstrated that GLP-1RAs are associated with significantly lower risks of pneumonia and severe sepsis in patients with type 2 diabetes compared to dipeptidyl peptidase-4 inhibitors (DPP-4is)
Keep in mind two important points when adding physical activity to your treatment protocol
Patients with a history of pancreatitis require particular caution, as GLP-1 receptor agonists have been associated with rare cases of acute pancreatitis
In contrast, these semaglutide-responsive proteins were not regulated in Glp1r VSM/ kidneys (Figure 7, DG)
Most of my patients are on it for the diagnosis of diabetes as well, so I dont have much experience with discontinuation
