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Across the STEP trials, semaglutide 2.4 mg consistently demonstrated statistically and clinically significant weight loss compared with placebo [13, 38,39,40,41,42,43,44,45,46]

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Only by achieving these strict preclinical milestones can nanomedicine safely and effectively transition from the bench to the bedside for patients with refractory osteosarcoma

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This suggests that tirzepatide has direct protective effects on the kidneys, which could be beneficial for patients with diabetic kidney disease