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Instead, they may be more effective as part of multimodal strategy that includes glycemic control, anti-inflammatory interventions, early enteral nutrition, and rehabilitation efforts aimed at preserving muscle mass and function in critically ill patients (59)
The honest framing: this is a promising but still-developing evidence base, much of it in cell and animal models rather than large human trials
Evid Based Complement Alternat Med
Alterations in brain hexokinase activity associated with heart failure in rats
Creatine's muscle-building effects are modest without proper stimulus and nutrition
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