The new findings add to a growing body of research suggesting that GLP-1 receptor agonists may influence mental health as well as metabolic health
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To interrogate the reliability of our findings, we performed western blot analysis in a separate CSDS cohort for the only protein affected in all three brain regions and the top affected protein in the NAc, RPRD2 (regulation of nuclear pre-mRNA domain containing 2), which plays an important role in gene transcription and was predicted to be elevated in resilient animals relative to susceptible in the NAc
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Maintaining intestinal barrier integrity is therefore essential to prevent LPS translocation and limit disease progression ( 3 Natural bioactive compounds advancing emerging therapeutics across chronic diseases Medicinal plants contain bioactive compounds like triterpenoids and curcumin, which possess significant therapeutic potential against major diseases
