Importantly, there were no cardiovascular adverse events, no clinically significant changes in blood pressure or heart rate, no alterations in thyroid function, no immunogenicity with no anti-AOD-9604 antibodies detected, and no signs of tolerance or receptor desensitization
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EMT, epithelial-mesenchymal transition
Additionally, the review will discuss the primary sources of oxidative stress in spermatozoa, including mitochondrial dysfunction, leukocyte activation, and environmental/lifestyle factors