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TT-OAD2 exhibits biased agonism, and kinetics of G-protein activation and signalling that are distinct from peptide agonists
Bone Marrow Transplant 6 Suppl 1:127-30, 1990
It binds to toxins and neutralizes free radicals, protecting cells from oxidative damage
Blood 88(10):234a, 1996
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In models of PD, curcumin activates the PI3K/Akt signaling pathway, which is crucial for promoting neuronal survival, enhancing neurotrophic support and reducing inflammation and oxidative damage, thereby improving dopaminergic neuron integrity and motor behavior ( EGCG from green tea ( Camelia sinensis ) can reduce S aggregation and the loss of dopamine by inhibiting MAO-B and COMT
