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[8] It is also available as the fixed-dose combinations of sitagliptin/metformin (Janumet, Janumet XR) [8] and sitagliptin/simvastatin (Juvisync)
Mild side effects can include nausea, flushing, dizziness, and localized irritation at the injection site
A new depression scale designed to be sensitive to change
However, HbA1c, which reflects average glucose over 2-3 months, takes longer to show the full effect of treatment, typically showing maximum improvement around months 3-6
GLP-1 drugs only mask this dysregulation, and when their effect is removed, their food cravings soon return
Most patients notice visible changes within two to four weeks, with the most significant results appearing between weeks four and eight
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