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0.6-0.8% placebo), consistent with the rapid weight loss effect Thyroid C-cell tumors : As with all GLP-1R agonists, tirzepatide carries a boxed warning based on rodent thyroid C-cell tumor findings

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Soluble fiber sources like oatmeal, bananas, and cooked carrots slow intestinal transit and add bulk to stool, counteracting semaglutide's acceleration effect

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Current Clinical Evidence for GLP-1 Use in Prader-Willi Syndrome Published case series and small observational studies suggest that semaglutide and tirzepatide may reduce appetite and promote weight loss in PWS patients