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It reversed glucose dysregulation without detrimental effects on metabolically healthy animals and reduced body weight, lowered fasting blood glucose, decreased glycosylated hemoglobin (HbA1C), improved glucose tolerance, and protected pancreatic islet architecture in diabetic fatty Zucker rats 22,23,24

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Western blot Cells were harvested and proteins were extracted using cell lysis buffer supplemented with 0.3% phenylmethylsulfonyl fluoride and proteinase and phosphatase inhibitors

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