Sermorelin's FDA Journey: Approved, Discontinued, and Compounded Sermorelin acetate (Geref) was FDA-approved in 1997 for pediatric GHD 1 and in 1990 for diagnostic use.26 The manufacturer discontinued Geref in 2008 due to "manufacturing difficulties," not safety or efficacy concerns.12 In 2013, the FDA confirmed it wasn't withdrawn for safety/effectiveness, allowing for potential generic approvals.12 Currently, Sermorelin is primarily available as a compounded medication 3, which is permitted but not individually FDA-approved like mass-produced drugs.22 5.2
Lilly has not yet launched direct sales in Canada
Your personal tolerance for side effects and your insurance coverage will also play a major role
This doesnt mean these peptides cause cancer, but it does mean extra caution is warranted with certain categories, including: TB-500, because of its relationship to angiogenesis and cell migration Growth hormone or IGF-1-related peptides Other growth-promoting compounds This is especially important for anyone with active cancer, a recent cancer history, or a strong genetic predisposition to cancer
Bech EM, Martos-Maldonado MC, Wismann P, et al
It reliably raises serum B12 levels, resolves megaloblastic anemia, and, when started before irreversible damage, can reverse neurological symptoms