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36 FDA adverse event cases reported including 30 requiring cholecystectomy and 1 death [8] [15] Pancreatitis : Meta-analysis of 21 trials with 34,721 patients found no significantly increased acute pancreatitis risk (OR 0.7, 95% CI 0.5-1.2), though isolated case reports exist including rare fatal cases Ophthalmologic Concerns Diabetic retinopathy complications : SUSTAIN-6 showed higher complication rates (3% versus 1.8% placebo), attributed to rapid HbA1c reduction rather than drug-specific effect
Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: relation to transcobalamin and homocysteine concentration in blood
These medicines are highly effective and are helping many people, Ariaee says
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