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Moisturize to form a protective seal around skin: Avoid creams with retinol

A better understanding of the complex physiology of weight regulation and the role of intestinal hormones in regulating food intake, appetite, and glucose homeostasis led to the discovery of GLP- 1 receptor analogs as safe and effective treatments, initially for T2DM and more recently in higher doses to treat obesity (liraglutide 3 mg and semaglutide 2.4 mg)

PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats

This can lead to accidental dehydration, where you simply forget to drink because the urge isnt there

Sharma et al., 2020

Patients with loose or sagging skin may need additional skin-tightening treatments