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Brain GSH concentrations and investigating heterogeneity Brain GSH did not differ in AD (pooled SMD [95%CI] = 0.07 [1.29, 1.43], p =0.6) and MCI (pooled SMD [95%CI] = 0.43 [1.19, 0.33], p =0.26) compared to healthy controls

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312 Similarly, EMT contributes to oxaliplatin and cisplatin resistance in gastric and colorectal cancers, mediated by factors such as Rab31 (via the Stat3/MUC-1/Twist1 axis) and THBS2 CAFs (via COL8A1-driven PI3K/AKT signaling)

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Other potential adverse effects of high dose and long-term glutathione supplementation include: Lightening of hair colour: A logically expected effect since hair colour is dependent on the amount and type of melanin which may be altered by glutathione supplementation

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