6 January 2026 The Malaysian Obesity Society (MYOS) wishes to issue a public health warning regarding the increasing availability of unregulated GLP-1 receptor agonists (GLP-1RA) and GLP-1/GIP ( co-agonist compounds sold through online shopping platforms, social media, and non-medical channels
GLP-1 medications: Stimulate insulin release Act on brain receptors to increase satiety and suppress appetite Slow gastric emptying , making us feel full longer Alter reward pathways , reducing our drive to eat for pleasure rather than hunger [1][3][4] This reward-hacking effect is particularly interesting
Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue
This is a normal part of your body adjusting, and they typically settle quickly as your system adapts
So Brooke and I had a meeting
Fluids Barriers CNS 16(1):3 Errede M, Girolamo F, Ferrara G, Strippoli M, Morando S, Boldrin V et al (2012) Blood-brain barrier alterations in the cerebral cortex in experimental autoimmune encephalomyelitis