Its a very powerful tool for mechanistic studies, not a nutritional supplement
A landmark study published in Diabetes (Tolhurst et al., 2012) demonstrated that SCFAs stimulate GLP-1 secretion via the FFAR2 receptor, and that mice lacking this receptor showed significantly reduced SCFA-triggered GLP-1 release
It works by mimicking the action of ghrelin and binding to the growth hormone secretagogue receptor (GHSR) in the brain, which triggers the pituitary gland to release GH
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Because it came from a species that humans never encountered evolutionarily, our enzymes did not readily destroy it ( [83] ) ( [84] )
Current medications like Zepbound and Wegovy range from $1,000 to $1,500 monthly