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Clinical trial registration: identifier NCT06518343
Ferroptosis in non-alcoholic fatty liver disease/non-alcoholic fatty liver disease-hepatocellular carcinoma Metabolic changes and hepatocyte lip toxicity caused by the ectopic accumulation of free fatty acids (FFAs) in the liver are considered to be the principal causes of liver injury in patients with NAFLD (39)
Conversely, there is no evidence for accumulation of valproyl-CoA in brain tissue, suggesting that the effects of VPA in the CNS are independent of the formation of this metabolite [80]
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